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Does Mederma Really Work for Scars
From onion extract to scar gels with SPF, here’s what science says about Mederma’s effectiveness and whether it’s worth your time and money.

If you’ve ever looked in the mirror and felt self-conscious about a scar whether from acne, surgery, or a past injury you’re not alone. Scars can carry emotional weight, and the search for effective over-the-counter treatments often leads people to one of the most well-known options: Mederma.
Promising to reduce the appearance of scars over time, Mederma has become a popular choice. But does it actually deliver results that justify the cost and commitment? Let’s break down how it works, what research shows, and what alternatives are available.
What Is Mederma and How Does It Work?
Mederma’s active ingredient is Allium cepa, or onion extract a substance believed to have anti-inflammatory and antibacterial properties. Some early lab-based research suggested that onion extract could improve collagen organization during wound healing, but these findings were based on animal studies, not humans.
- Onion extract may reduce inflammation, which theoretically helps scars appear smoother. 
- However, clinical trials in humans haven’t shown consistent or significant improvements in scar appearance when compared to basic moisturizers or petroleum jelly. 
How to Use Mederma
Mederma is safe for adults and children aged six months and up, but it's only appropriate once a wound has fully closed. For best results, the manufacturer recommends applying it:
- Three times a day for eight weeks on new scars. 
- Three times a day for three to six months on older scars. 
It’s important to know that using Mederma is time-intensive and requires daily consistency. This can be a barrier for many users.
Pros of Mederma:
- Generally safe and well-tolerated 
- Available without a prescription 
- Comes in various forms including gel, cream, and oil 
- Some products include SPF 30 for sun protection 
Cons of Mederma:
- More expensive than alternatives like petroleum jelly 
- Scientific evidence is limited and inconsistent 
- Daily commitment required for months at a time 
- No proven benefit over simpler, more affordable scar treatments 
Does Mederma Help with Dark Spots?
Mederma may help fade dark spots related to scars, but it won't improve pigmentation issues caused by melanin, such as melasma, age spots, or sun spots. For those types of discoloration, treatments like hydroquinone, vitamin C serums, or retinoids are more effective.
What the Research Says
A 2012 study involving 44 participants found slight improvements in scar appearance, texture, and softness when Mederma was used regularly. However, the study was small and lacked a control group using a placebo cream or petroleum jelly.
In contrast, larger studies, including one published in 2006 and another in 2018, found no significant difference between onion extract-based creams and petroleum-based products.
Interestingly, one well-established principle in wound care is that moist wounds heal up to 50% faster than dry wounds. This may explain why any topical product, including petroleum jelly, can help improve scar appearance simply by maintaining skin hydration.
Popular Alternatives to Mederma
If you’re looking for over-the-counter options, consider these dermatologist-recommended alternatives:
- Silicone-based products: - ScarAway Silicone Sheets 
- Kelo-cote Advanced Scar Gel 
- bioCorneum + SPF 30 
 
- Other treatments your provider may suggest: - Laser therapy for flattening raised scars 
- Chemical peels or dermabrasion to smooth skin texture 
- Filler injections for pitted or indented scars 
- Prescription creams for discoloration 
- Minor surgical procedures for acne scarring 
 
Should You Try Mederma?
If you’re curious and consistent, Mederma is unlikely to do any harm and some users do report modest improvements in scar appearance. But if you're looking for a more evidence-backed solution, silicone-based gels or sheets remain the gold standard in topical scar therapy.
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