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Struggling with Low Iron? Here’s What Happened When I Tried Iron Infusions

How iron infusions turned my exhaustion into energy and why they remain under-prescribed.

Dealing with persistent fatigue, breathlessness, and dizziness often feels like a mystery to solve. For years, I struggled with low iron levels, trying everything from pills to diet changes to boost my iron. But nothing seemed to stick until I tried iron infusions. Here’s my journey, what I learned, and why this treatment is often overlooked despite its benefits.

My Struggle with Low Iron Levels

The signs of iron deficiency were subtle at first. After my second miscarriage in 2018, my bloodwork revealed low red blood cell and hemoglobin levels, but I brushed it off, hoping prenatal vitamins would be enough. Over the next few years, fatigue returned, and by 2024, it hit a breaking point. Falling asleep at work, struggling to climb stairs, and tightness in my chest made it clear I needed real help.

Blood tests confirmed severe anemia, and I couldn’t tolerate the nausea caused by over-the-counter (OTC) iron pills. Despite my efforts to eat more iron-rich foods like steak and spinach, my symptoms worsened. That’s when I decided to explore iron infusions.

What Are Iron Infusions?

Iron infusions deliver supplemental iron directly into the bloodstream via an IV. They are typically reserved for those who:

  • Can’t tolerate oral iron supplements due to side effects like nausea or constipation.

  • Have difficulty absorbing iron because of conditions like celiac disease, inflammatory bowel disease, or gastrointestinal surgery.

“The goal is to replenish iron stores efficiently and bypass the gut,” says Ariela Marshall, MD, a hematologist at the University of Minnesota. While dietary changes and supplements may work for mild cases, severe iron deficiency often requires more direct intervention.

My Experience with Iron Infusions

Fast and Simple Treatment

I visited a hematologist, who recommended Venofer, a low-dose form of iron sucrose. My first session took just 35 minutes, with no major side effects besides slightly darker urine. For others, side effects like nausea or headaches may occur, though allergic reactions are rare with modern formulations.

My treatment plan included three more infusions spaced one to two weeks apart, with adjustments based on my bloodwork and symptoms.

The Results

Within a week of my first infusion, I felt noticeably better. Restless leg syndrome (a common symptom of iron deficiency) eased, and my energy levels soared. Climbing stairs no longer left me winded, and my runs felt smoother. Blood tests confirmed that my red blood cell count, hemoglobin, and ferritin levels were climbing still not perfect, but finally on the right track.

Why Are Iron Infusions Under-Prescribed?

Despite their effectiveness, iron infusions are often overlooked for several reasons:

1. Outdated Safety Concerns

Older formulations of IV iron carried risks of severe allergic reactions, but modern versions have significantly reduced these risks. “The additives were the problem, not the iron itself,” explains Dr. Marshall.

2. Cost Barriers

Iron infusions can be expensive, with costs ranging from hundreds to thousands of dollars per session. While insurance may cover part of the expense, coverage varies widely.

3. Misdiagnosed or Missed Deficiency

Iron deficiency symptoms fatigue, dizziness, and breathlessness are often dismissed as stress or aging. Many doctors also don’t routinely check ferritin levels during standard bloodwork, and if levels are borderline low, they may not consider treatment necessary.

What to Do If You Suspect Low Iron

If you’re experiencing symptoms of iron deficiency, it’s important to advocate for yourself:

  • Request a Blood Test: Ask your doctor for an iron panel, including ferritin levels.

  • Consult a Specialist: If your symptoms persist or OTC supplements don’t help, see a hematologist. Recommendations from friends or online reviews can help you find a trusted provider.

  • Avoid Self-Diagnosing: While understanding your lab results is helpful, only a doctor can provide an accurate diagnosis and treatment plan.

Lessons Learned

For me, iron infusions were a game-changer. But they’re not a standalone solution. Identifying the root cause of your iron deficiency is critical whether it’s heavy periods, dietary issues, or an underlying medical condition.

“It’s like pouring water into a leaky bucket,” says Dr. Marshall. “You need to fix the leak.”

If you’ve been dismissed or feel like your symptoms aren’t taken seriously, trust your instincts. Seek out care that listens to your concerns and works to restore your health.

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