How Refined Sugar Affects Your Body

From energy crashes to skin breakouts, here's how added sugar affects everything from your brain to your gut and what you can do to cut back.

Refined sugar is practically everywhere hidden in sauces, cereals, yogurts, beverages, and, of course, your favorite desserts. While it’s easy to indulge without realizing just how much you're consuming, the impact of refined sugar on your body can be far-reaching and surprisingly intense.

The average American eats nearly 17 teaspoons of added sugar each day “almost three times” the daily recommended limit for women, according to the University of California San Francisco. So what’s really going on inside your body when you eat that cookie or sip that sugary latte? Let’s break it down.

Your Brain: Sugar Feeds Cravings and Mood Swings

Refined sugar stimulates your brain’s reward system in a powerful way. Studies show that high sugar intake can actually alter your brain chemistry, leading to cravings and behavior similar to addiction. One study from The American Journal of Clinical Nutrition linked high sugar consumption to a 23% higher risk of clinical depression in women, with similar findings in men.

Your Teeth: Cavities Are Just the Beginning

Refined sugar doesn't directly rot your teeth it feeds harmful bacteria that do. These bacteria form sticky plaque and release acids that wear down enamel, significantly increasing your risk for cavities. A 2016 study in the Journal of Dental Research found that high sugar consumers had a 66% greater prevalence of cavities than low sugar consumers.

Your Heart: Sugar Overload Can Be Deadly

Too much added sugar is a major contributor to cardiovascular disease. A study in JAMA Internal Medicine found that people who got 17–21% of their calories from added sugar had a 38% higher risk of dying from heart disease. Excess sugar is stored as liver fat, which raises triglycerides and LDL (bad) cholesterol while lowering HDL (good) cholesterol all red flags for your heart.

Your Liver: Fructose Is Especially Harmful

Refined sugars particularly those high in fructose like high-fructose corn syrup are metabolized in the liver, where they can be converted into fat. Over time, this process may contribute to non-alcoholic fatty liver disease (NAFLD), as highlighted in a 2018 Journal of Hepatology study.

Your Energy: Sugar Highs Lead to Sugar Crashes

Refined sugar gives you a quick burst of energy, but the spike is quickly followed by a steep crash. This drop in blood sugar can leave you feeling irritable, tired, and hungry again soon after eating setting up a cycle that’s hard to break.

Your Hormones: Insulin Resistance Is a Major Risk

Over time, consistently high sugar intake can lead to insulin resistance, a condition where your body stops responding to insulin properly. A study in Obesity found that just one week of excessive refined sugar was enough to reduce insulin sensitivity in men raising the risk of type 2 diabetes and metabolic syndrome.

Your Weight: It Adds Up Fast

Sugar’s impact on insulin, hunger, and fat storage makes it a key player in weight gain. A 2013 review in the BMJ found that increasing sugar intake was associated with a weight gain of 1.7 pounds in less than 8 weeks and over 6 pounds beyond that. Excess glucose is often stored as body fat, especially when not needed for energy.

Your Gut: Sugar Disrupts the Microbiome

Refined sugar alters the balance of bacteria in your gut, promoting the overgrowth of harmful microbes and reducing overall microbial diversity. This imbalance may contribute to inflammation, digestion issues, and even a weakened immune system, per a 2012 review in Obesity Reviews.

Your Skin: Breakouts and Premature Aging

Excess sugar is linked to acne and dull, puffy skin. Elevated insulin levels increase oil production, while sugar-fueled inflammation can worsen breakouts. Additionally, sugar contributes to the formation of advanced glycation end products (AGEs), which damage collagen and elastin key proteins that keep skin firm and youthful.

How to Cut Back on Refined Sugar

Reducing refined sugar doesn’t mean you have to eliminate sweetness from your life. Small, sustainable changes can go a long way:

  • Ditch sugary drinks: Nearly half of added sugar intake comes from beverages. Swap soda and sweetened coffees for water, herbal tea, or sparkling water.

  • Read labels carefully: Look for “added sugars” on nutrition labels, and scan ingredients for syrups, juices, or anything ending in “-ose.”

  • Snack smart: Reach for snacks that combine complex carbs with protein, like yogurt with berries and nuts.

  • Satisfy sweet cravings naturally: Fruit is a great source of natural sugar plus fiber, vitamins, and antioxidants choose whole fruits over fruit juices or syrups.

  • Use spices instead of sugar: Cinnamon, nutmeg, ginger, and vanilla can add flavor without the sugar spike.

Refined sugar may be tasty, but it can take a toll on nearly every system in your body. From your mental health and metabolism to your skin and gut, the effects are cumulative and significant. But with mindful choices and small adjustments, you can take control of your sugar intake and support your health long-term.

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